10-year ASCVD risk (Pooled Cohort Equations)
ACC/AHA 2013 estimate of 10-year risk of heart attack or stroke for adults 40 to 79 without ASCVD.
Inputs
4 of 9SexUsed by the equation
years
Race (as used by the equation)
mmHg
Treated for high BP
Diabetes
Current smoker
Patient values are shared with every calculator.
When to use
- Primary prevention statin discussions in adults 40 to 79 with LDL 70 to 189 mg/dL and no diabetes-only indication.
Pearls and pitfalls
- The equations include race; the AHA PREVENT equations (2023) are race-free and add kidney function.
- Tends to overestimate risk in many contemporary populations.
- Not for patients with known ASCVD or LDL of 190 or higher (already statin candidates).
Why use
The equation behind the 2018 cholesterol guideline's risk categories.
Risk = 1 − S₀^exp(Σβx − mean), with sex- and race-specific coefficients (Goff 2014)