Clinical Pulmonary Infection Score (CPIS)
Likelihood of ventilator-associated pneumonia.
Inputs
CompleteTemperature (°C)
WBC (×10³/µL)
Tracheal secretions
Oxygenation
Chest X-ray
Tracheal aspirate culture
Worked calculation
Your values are highlighted.
- Points
When to use
- Ventilated patients with new infiltrates.
Pearls and pitfalls
- Above 6 suggests VAP; CPIS 6 or lower at day 3 supported stopping antibiotics in the Singh trial.
- Limited accuracy; use with clinical judgment.
Why use
Supports antibiotic stewardship in the ICU.
| Criterion | Points |
|---|---|
| Temperature (°C): 36.5–38.4 | 0 |
| 38.5–38.9 | +1 |
| 39 or higher, or 36 or lower | +2 |
| WBC (×10³/µL): 4–11 | 0 |
| Below 4 or above 11 | +1 |
| Below 4 or above 11 with bands 50% or more | +2 |
| Tracheal secretions: None or scant | 0 |
| Nonpurulent | +1 |
| Purulent | +2 |
| Oxygenation: PaO₂/FiO₂ above 240, or ARDS | 0 |
| PaO₂/FiO₂ 240 or lower, no ARDS | +2 |
| Chest X-ray: No infiltrate | 0 |
| Diffuse or patchy infiltrate | +1 |
| Localized infiltrate | +2 |
| Tracheal aspirate culture: No or light growth | 0 |
| Moderate or heavy growth | +1 |
| Same organism on Gram stain too | +2 |