DAS28 (rheumatoid arthritis disease activity)
28-joint disease activity score with ESR or CRP.
Inputs
1 of 5joints
joints
Marker
value
mm (0–100)
When to use
- Treat-to-target monitoring in RA.
Pearls and pitfalls
- Remission below 2.6; low 2.6–3.2; moderate 3.2–5.1; high above 5.1.
- DAS28-CRP runs lower than DAS28-ESR.
Why use
The most used RA activity measure in trials.
ESR: 0.56√TJC + 0.28√SJC + 0.70 ln(ESR) + 0.014 × patient global; CRP: 0.56√TJC + 0.28√SJC + 0.36 ln(CRP mg/L + 1) + 0.014 × global + 0.96