Fomepizole dosing (toxic alcohols)

Loading and maintenance doses for methanol or ethylene glycol poisoning, including during dialysis.

Previewv0.1.0 · Pending clinical review

Inputs

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Actual (total) body weight
When to use
  • Suspected methanol or ethylene glycol ingestion.
Pearls and pitfalls
  • Continue until the toxic alcohol level is below 20 mg/dL and the patient is asymptomatic with normal pH.
  • Dialysis removes fomepizole; dose every 4 hours during hemodialysis.
Why use

Weight-based doses for every phase.

15 mg/kg load; 10 mg/kg every 12 h × 4 doses; then 15 mg/kg every 12 h; every 4 h during hemodialysis

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