ISTH overt DIC score
Diagnoses overt disseminated intravascular coagulation.
Inputs
CompletePlatelets (× 10⁹/L)
D-dimer or fibrin markers
PT prolongation
Fibrinogen
Worked calculation
Your values are highlighted.
- Points
When to use
- Only with an underlying disorder known to cause DIC.
Pearls and pitfalls
- 5 or higher: compatible with overt DIC; repeat daily. Below 5: suggestive of non-overt DIC; repeat in 1–2 days.
Why use
The international standard definition.
| Criterion | Points |
|---|---|
| Platelets (× 10⁹/L): Above 100 | 0 |
| 50–100 | +1 |
| Below 50 | +2 |
| D-dimer or fibrin markers: No increase | 0 |
| Moderate increase | +2 |
| Strong increase | +3 |
| PT prolongation: Under 3 s | 0 |
| 3–6 s | +1 |
| Over 6 s | +2 |
| Fibrinogen: 1 g/L or higher | 0 |
| Below 1 g/L | +1 |