PECARN rule for febrile infants 29–60 days
Identifies febrile infants at low risk of serious bacterial infection.
Inputs
0 of 2Positive urinalysis (leukocyte esterase, nitrite, or pyuria)
cells/µL
ng/mL
When to use
- Well-appearing febrile infants 29–60 days.
Pearls and pitfalls
- Not for infants 28 days or younger (full workup per AAP 2021).
- AAP 2021 guideline uses similar inflammatory marker thresholds.
Why use
Avoids lumbar puncture in low-risk infants.
Low risk if urinalysis negative, ANC ≤ 4,090/µL, and procalcitonin ≤ 0.5 ng/mL