SCORTEN for toxic epidermal necrolysis
Mortality in Stevens-Johnson syndrome and toxic epidermal necrolysis.
Inputs
Age 40 or older
Malignancy
Heart rate 120 or higher
Epidermal detachment above 10% BSA on day 1
BUN above 28 mg/dL (10 mmol/L urea)
Glucose above 252 mg/dL (14 mmol/L)
Bicarbonate below 20 mEq/L
Worked calculation
Your values are highlighted.
- Points
When to use
- Within 24 hours of admission, and again on day 3.
Pearls and pitfalls
- Stop the culprit drug immediately; common culprits include allopurinol, anticonvulsants, sulfonamides, lamotrigine, and nevirapine.
Why use
Standard SJS/TEN prognosis.
| Criterion | Points |
|---|---|
| Age 40 or older | +1 |
| Malignancy | +1 |
| Heart rate 120 or higher | +1 |
| Epidermal detachment above 10% BSA on day 1 | +1 |
| BUN above 28 mg/dL (10 mmol/L urea) | +1 |
| Glucose above 252 mg/dL (14 mmol/L) | +1 |
| Bicarbonate below 20 mEq/L | +1 |