SIRS criteria
Systemic inflammatory response syndrome: 2 or more criteria.
Inputs
Temperature above 38 °C or below 36 °C
Heart rate above 90
Respiratory rate above 20 or PaCO₂ below 32 mmHg
WBC above 12,000 or below 4,000/µL, or more than 10% bands
Worked calculation
Your values are highlighted.
- Criteria present
When to use
- Screening for systemic inflammation.
Pearls and pitfalls
- Sepsis-3 replaced SIRS with SOFA-based definitions, but many screening protocols still use SIRS.
- Two or more criteria meet SIRS.
Why use
Still embedded in many hospital sepsis alerts.
Positive if any criterion is present