Augmented renal clearance (ARC) risk score
Identifies ICU patients likely to have CrCl of 130 mL/min or more despite a normal creatinine.
Inputs
Age 50 or younger
Trauma admission
Modified SOFA 4 or less
Worked calculation
Your values are highlighted.
- Points
When to use
- Young or trauma ICU patients on renally cleared antimicrobials.
Pearls and pitfalls
- Estimating equations underestimate clearance in ARC; a measured 8-hour urine creatinine clearance is best.
- Consider higher or extended-infusion beta-lactam dosing and early levels.
Why use
Flags patients at risk of subtherapeutic antibiotic exposure.
| Criterion | Points |
|---|---|
| Age 50 or younger | +6 |
| Trauma admission | +3 |
| Modified SOFA 4 or less | +1 |