CISNE score for febrile neutropenia
Complications in clinically stable solid-tumor patients with febrile neutropenia.
Inputs
ECOG performance status 2 or higher
COPD
Chronic cardiovascular disease
Mucositis grade 2 or higher
Monocytes below 200/µL
Stress-induced hyperglycemia
Worked calculation
Your values are highlighted.
- Points
When to use
- Stable adults with solid tumors and febrile neutropenia after mild chemotherapy.
Pearls and pitfalls
- Endorsed by ASCO/IDSA 2018 for stable solid-tumor patients.
Why use
Better discrimination than MASCC in stable patients.
| Criterion | Points |
|---|---|
| ECOG performance status 2 or higher | +2 |
| COPD | +1 |
| Chronic cardiovascular disease | +1 |
| Mucositis grade 2 or higher | +1 |
| Monocytes below 200/µL | +1 |
| Stress-induced hyperglycemia | +2 |