Kidney Failure Risk Equation (4-variable)
2- and 5-year risk of kidney failure in CKD stages 3–5.
Inputs
1 of 5SexUsed by the equation
years
mL/min/1.73 m²
Region
Patient values are shared with every calculator.
When to use
- Adults with eGFR below 60 (CKD G3–G5).
Pearls and pitfalls
- KDIGO 2024: refer to nephrology at 5-year risk 3–5% or higher; plan kidney replacement therapy at 2-year risk above 40%.
- Use UACR in mg/g.
Why use
Validated in over 700,000 patients worldwide.
L = −0.2201(age/10 − 7.036) + 0.2467(male − 0.5642) − 0.5567(eGFR/5 − 7.222) + 0.4510(ln UACR − 5.137); risk = 1 − S₀^exp(L); North America S₀ 0.9750 (2 y), 0.9240 (5 y); elsewhere 0.9832, 0.9365