MDRD study eGFR (IDMS-traceable, 4-variable)
The 4-variable MDRD estimate still used in some drug labels and older protocols.
Inputs
0 of 3SexUsed by the equation
years
Stable value
When to use
- A label or protocol specifically references MDRD.
Pearls and pitfalls
- CKD-EPI 2021 is preferred for CKD staging.
- The original equation included a race coefficient; ClinDose does not apply it, consistent with current KDIGO and NKF-ASN guidance.
- Underestimates GFR above 60.
Why use
Some older references still use it.
eGFR = 175 × SCr^−1.154 × age^−0.203 × 0.742 (female)