Cephalexin
Quoted from the FDA label. Product labels differ by manufacturer and change over time; confirm against the label for the product you are using. Not yet reviewed by a ClinDose pharmacist.
Dosing in kidney impairment
Recommended Dosage in Adult and Pediatric Patients at Least 15 Years of Age with Renal Impairment Administer the following dosing regimens for cephalexin capsules USP to patients with renal impairment [ see WARNINGS AND PRECAUTIONS and USE IN SPECIFIC POPULATIONS]. See Table 1 for dosage in adults and pediatric patients at least 15 years of age with renal impairment.
There is insufficient information to recommend dosage adjustment for pediatric patients younger than 15 years of age with renal impairment. Table 1. Recommended Cephalexin Capsules Dosage for Adults Patients and Pediatric Patients (at Least 15 Years of Age) with Renal Impairment [See table below.]
| Renal function (Creatinine Clearance) | Dosage recommendation |
| Greater than or equal to 60 mL/min | No dosage adjustment |
| 30 mL/min to 59 mL/min | No dosage adjustment; maximum daily dose should not exceed 1 g |
| 15 mL/min to 29 mL/min | 250 mg, every 8 hours or every 12 hours |
| 5 mL/min to 14 mL/min not yet on dialysisThere is insufficient information to make dose adjustment recommendations in patients on hemodialysis | 250 mg, every 24 hours |
| 1 mL/min to 4 mL/min not yet on dialysis | 250 mg, every 48 hours or every 60 hours |