Ropinirole
Quoted from the FDA label. Product labels differ by manufacturer and change over time; confirm against the label for the product you are using. Not yet reviewed by a ClinDose pharmacist.
Dosing in kidney impairment
Renal Impairment No dose adjustment is necessary in patients with moderate renal impairment (creatinine clearance of 30 to 50 mL/min). For patients with end-stage renal disease on hemodialysis, a reduced maximum dose is recommended [see Dosage and Administration (2.2, 2.3), Clinical Pharmacology] . The use of ropinirole in patients with severe renal impairment (creatinine clearance 30 mL/min) without regular dialysis has not been studied.
Dosing in liver impairment
Hepatic Impairment The pharmacokinetics of ropinirole have not been studied in patients with hepatic impairment.