Sulfamethoxazole and trimethoprim
Quoted from the FDA label. Product labels differ by manufacturer and change over time; confirm against the label for the product you are using. Not yet reviewed by a ClinDose pharmacist.
Dosing in kidney impairment
The following table is a guideline for the attainment of this dosage: Children 2 months of age or older: 1 For Patients with Impaired Renal Function When renal function is impaired, a reduced dosage should be employed using the following table: [See table below.] Acute Exacerbations of Chronic Bronchitis in Adults The usual adult dosage in the treatment of acute exacerbations of chronic bronchitis is 1 sulfamethoxazole and trimethoprim DS (double strength) tablet or 2 sulfamethoxazole and trimethoprim tablets every 12 hours for 14 days.
| Creatinine Clearance (mL/min) | Recommended Dosage Regimen |
| Above 30 15–30 Below 15 | Usual standard regimen ½ the usual regimen Use not recommended |