Reynolds Risk Score
10-year cardiovascular risk including hsCRP and family history.
Inputs
0 of 6SexUsed by the equation
years
mm Hg
Current smoker
Parent with MI before age 60
Leave blank if not diabetic.
%
Patient values are shared with every calculator.
When to use
- Nondiabetic adults 45–80 without CVD (women's model allows diabetes via HbA1c).
Pearls and pitfalls
- Family history means a parent with MI before age 60.
- US guidelines favor PREVENT or the pooled cohort equations; Reynolds can refine borderline decisions.
Why use
Adds inflammation and family history.
Women: B = 0.0799·age + 3.137·ln(SBP) + 0.180·ln(hsCRP) + 1.382·ln(TC) − 1.172·ln(HDL) + 0.134·HbA1c (if diabetic) + 0.818·smoker + 0.438·FHx; risk = 1 − 0.98634^exp(B − 22.325). Men: B = 4.385·ln(age) + 2.607·ln(SBP) + 0.102·ln(hsCRP) + 0.963·ln(TC) − 0.772·ln(HDL) + 0.405·smoker + 0.541·FHx; risk = 1 − 0.8990^exp(B − 33.097)