Iron sucrose

Adult Patients with Hemodialysis Dependent-Chronic Kidney Disease (HDD-CKD) Administer Iron Sucrose Injection 100 mg undiluted as a slow intravenous injection over 2 to 5 minutes, or as an infusion of 100 mg diluted in a maximum of 100 mL of 0.9% NaCl over a period of at least 15 minutes, per consecutive hemodialysis session [ see How Supplied/Storage and Handling ] .

Administer Iron Sucrose Injection early during the dialysis session (generally within the first hour). The usual total treatment course of Iron Sucrose Injection is 1000 mg. Iron Sucrose Injection treatment may be repeated if iron deficiency reoccurs.

Adult Patients with Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD) Administer Iron Sucrose Injection 200 mg undiluted as a slow intravenous injection over 2 to 5 minutes or as an infusion of 200 mg in a maximum of 100 mL of 0.9% NaCl over a period of 15 minutes. Administer on 5 different occasions over a 14 day period.

There is limited experience with administration of an infusion of 500 mg of Iron Sucrose Injection, diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14 [ see How Supplied/Storage and Handling ] . Iron Sucrose Injection treatment may be repeated if iron deficiency reoccurs.

Adult Patients with Peritoneal Dialysis Dependent-Chronic Kidney Disease (PDD-CKD) Administer Iron Sucrose Injection in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. Dilute Iron Sucrose Injection in a maximum of 250 mL of 0.9% NaCl [ see How Supplied/Storage and Handling ] .

Iron Sucrose Injection treatment may be repeated if iron deficiency reoccurs.

Mode of Administration Administer Iron Sucrose Injection only intravenously by slow injection or by infusion. The dosage of Iron Sucrose Injection is expressed in mg of elemental iron. Each mL contains 20 mg of elemental iron.