Coding and coverage · ICD-10-CM

C92 › C92.0

C92.02 Acute myeloblastic leukemia, in relapse

BillableCMS-HCC V28: HCC 17Chapter 2
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Instructional notes

Chapter 2

Notes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

C92

Excludes1Not coded here: never report with this code, except when the two conditions are unrelated.
  • personal history of leukemia (Z85.6)
Code also
  • , if applicable, pancytopenia (acquired) (D61.818)
Includes
  • granulocytic leukemia
  • myelogenous leukemia

C92.0

Excludes1Not coded here: never report with this code, except when the two conditions are unrelated.
  • acute exacerbation of chronic myeloid leukemia (C92.10)
  • refractory anemia with excess of blasts not in transformation (D46.2-)
Inclusion terms
  • Acute myeloblastic leukemia, minimal differentiation
  • Acute myeloblastic leukemia (with maturation)
  • Acute myeloblastic leukemia 1/ETO
  • Acute myeloblastic leukemia M0
  • Acute myeloblastic leukemia M1
  • Acute myeloblastic leukemia M2
  • Acute myeloblastic leukemia with t(8;21)
  • Acute myeloblastic leukemia (without a FAB classification) NOS
  • Refractory anemia with excess blasts in transformation [RAEB T]

Chapter 2: Neoplasms · C00-C96 Malignant neoplasms (C00-C96)

Source: ICD-10-CM FY 2027 code descriptions and tabular list (CMS and CDC National Center for Health Statistics), effective 2026-10-01 through 2027-09-30 · CMS ICD-10 files. HCC mapping: CMS-HCC V28, payment year 2027. As of 2026-11-04.

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