Coding and coverage · ICD-10-CM

Z15

Z15.8 Genetic susceptibility to other disease

Not billable (header)Chapter 21

Report one of the more specific codes below.

Codes under this one

  • Z15.81 Genetic susceptibility to multiple endocrine neoplasia [MEN]
  • Z15.89 Genetic susceptibility to other disease

Instructional notes

Chapter 21

Notes
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
  • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
  • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Z15

Excludes1Not coded here: never report with this code, except when the two conditions are unrelated.
Use additional codeAdd a second code for the full picture.
  • code, if applicable, for any associated family history of the disease (Z80-Z84)
Includes
  • confirmed abnormal gene

Chapter 21: Factors influencing health status and contact with health services · Z14-Z15 Genetic carrier and genetic susceptibility to disease (Z14-Z15)

Source: ICD-10-CM FY 2027 code descriptions and tabular list (CMS and CDC National Center for Health Statistics), effective 2026-10-01 through 2027-09-30 · CMS ICD-10 files. HCC mapping: CMS-HCC V28, payment year 2027. As of 2026-11-04.

Coverage and payment depend on the claim details; confirm with the Medicare Administrative Contractor.