Enoxaparin renal and weight adjustment
Use as a template
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ClinDose template, review and adapt before use
Renal dosing table
| CrCl (mL/min) | Dose |
|---|---|
| 30 and above | Usual dose for the indication. The label recommends no dose adjustment for creatinine clearance 30 to 50 mL/min and 50 to 80 mL/min; observe for bleeding.PlaceholderFDA label |
| 0 to 29 | Prophylaxis: 30 mg administered subcutaneously once daily; Treatment: 1 mg/kg administered subcutaneously once dailyFDA label |
Severe renal impairment doses are quoted from Table 1 of the FDA label.
Weight-based dosing
Dose per kg set by your institution, per indication, using actual body weight.
Set dose caps or anti-Xa monitoring for high or low body weight per your institution.
Monitoring
- Anti-Xa levelWhen and for whom set by your institutionTarget Range set by your institutionPlaceholder
- Platelet countFrequency set by your institutionPlaceholder
Sources
- FDA label for enoxaparin (DailyMed), dosage in renal impairment, effective 2026-05-28