Piperacillin-tazobactam extended infusion
Use as a template
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ClinDose template, review and adapt before use
Extended infusion is an institutional practice and is not described in the FDA label. Enter your regimen for each kidney function band.
Renal dosing table
| CrCl (mL/min) | Dose |
|---|---|
| Above 40 | Extended-infusion regimen set by your institutionPlaceholder |
| 20 to 40 | Extended-infusion regimen set by your institutionPlaceholder |
| 0 to 19 | Extended-infusion regimen set by your institutionPlaceholder |
Kidney function bands follow the FDA label's table.
Protocol document
FDA label table (30-minute infusion), for reference
- Greater than 40 mL/min: All Indications (except nosocomial pneumonia): 3.375 g every 6 hours; Nosocomial Pneumonia: 4.5 g every 6 hours
- 20 to 40 mL/min: All Indications (except nosocomial pneumonia): 2.25 g every 6 hours; Nosocomial Pneumonia: 3.375 g every 6 hours
- Less than 20 mL/min: All Indications (except nosocomial pneumonia): 2.25 g every 8 hours; Nosocomial Pneumonia: 2.25 g every 6 hours
Sources
- FDA label for piperacillin and tazobactam (DailyMed), dosage in renal impairment, effective 2026-05-08