Technetium tc-99m sodium pertechnetate
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From MedlinePlus, U.S. National Library of Medicine
Radioactive Diagnostic Agent
Dosing in kidney impairment
| Organ | Absorbed Radiation Dose (mGy) for a 1110 MBq (30mCi) dose |
|---|---|
| To obtain radiation absorbed dose in rads (30 mCi dose) from the above table, divide individual organ values by a factor of 10 (does not apply for effective dose). | |
| Adrenals | 4.1 |
| Urinary Bladder Wall | 20 |
| Bone Surfaces | 6.2 |
| Brain | 2.2 |
| Breasts | 2 |
| Gallbladder Wall | 8.3 |
| Stomach Wall | 29 |
| Small Intestine | 18 |
| ULI Wall | 63 |
| LLI Wall | 23 |
| Heart Wall | 3.5 |
| Kidneys | 6 |
| Liver | 4.7 |
| Lungs | 2.9 |
| Muscle | 3.6 |
| Ovaries | 11 |
| Pancreas | 6.3 |
| Red Marrow | 4.1 |
| Skin | 2 |
| Spleen | 4.8 |
| Testes | 3.1 |
| Thymus | 2.7 |
| Thyroid | 24 |
| Uterus | 9 |
| Remaining Tissues | 3.9 |
| Effective Dose (mSv) | 14 |
| Age | 15 years | 10 years | 5 years | 1 year |
|---|---|---|---|---|
| To obtain radiation absorbed dose in rads (30 mCi dose) from the above table, divide individual organ values by a factor of 10 (does not apply for effective dose). | ||||
| Administered activity in MBq (mCi) | 1110 (30) | 740 (20) | 555 (15) | 370 (10) |
| Organ | ||||
| Adrenals | 5.3 | 5.4 | 6.2 | 7.1 |
| Urinary Bladder Wall | 26 | 22 | 18 | 22 |
| Bone Surfaces | 7.6 | 7.5 | 8.1 | 10 |
| Brain | 2.8 | 3.1 | 3.7 | 4.5 |
| Breasts | 2.6 | 2.6 | 3.2 | 4.1 |
| Gallbladder Wall | 11 | 12 | 13 | 13 |
| Stomach Wall | 38 | 36 | 43 | 59 |
| Small Intestine | 22 | 23 | 26 | 30 |
| ULI Wall | 81 | 89 | 110 | 140 |
| LLI Wall | 31 | 33 | 40 | 48 |
| Heart Wall | 4.5 | 4.6 | 5.2 | 6.4 |
| Kidneys | 7.2 | 6.9 | 7.8 | 8.5 |
| Liver | 6 | 6.7 | 8 | 9.1 |
| Lungs | 3.8 | 3.8 | 4.4 | 5.3 |
| Muscle | 4.5 | 4.5 | 5 | 6 |
| Ovaries | 14 | 13 | 14 | 17 |
| Pancreas | 8.1 | 8.2 | 8.9 | 10 |
| Red Marrow | 5.1 | 5 | 5.2 | 6 |
| Skin | 2.5 | 2.6 | 3.2 | 3.8 |
| Spleen | 6 | 6 | 6.7 | 7.8 |
| Testes | 4.1 | 4.3 | 4.9 | 6 |
| Thymus | 3.6 | 3.5 | 4.2 | 5.3 |
| Thyroid | 40 | 41 | 67 | 81 |
| Uterus | 11 | 11 | 12 | 14 |
| Remaining Tissues | 4.8 | 4.8 | 5.4 | 6.4 |
| Effective Dose (mSv) | 19 | 19 | 23 | 29 |
Preparation and administration
Prepare this dose
Your numbers for technetium tc-99m sodium pertechnetate. Take vial strength, diluent, and limits from the label below.
Enter a dose to see draw volume, final concentration, and rates.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit. The solution to be administered as the patient dose should be clear and contain no particulate matter. Do not use an eluate of the TECHNELITE ® , Technetium Tc 99m Generator later than one working day after elution (12 hours).
Contraindications
CONTRAINDICATIONS: None known.
Safety data
Reported adverse events (FAERS)
Liver injury (LiverTox)
LiverTox has no chapter for technetium tc-99m sodium pertechnetate. Check the label's hepatic warnings.
Pregnancy and lactation
Pregnancy
Pregnancy Animal reproductive studies have not been conducted with Sodium Pertechnetate Tc 99m. It is also not known whether Sodium Pertechnetate Tc 99m can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Sodium Pertechnetate Tc 99m Injection should be given to a pregnant woman only if clearly needed. Ideally examinations using radiopharmaceuticals, especially those elective in nature, of a woman of childbearing capability should be performed during the first few (approximately 10) days following the onset of menses.
Lactation
Nursing Mothers Sodium Pertechnetate Tc 99m is excreted in human milk during lactation; therefore formula feedings should be substituted for breast feeding. This radiopharmaceutical preparation should not be administered to pregnant or lactating women unless expected benefits to be gained outweigh the potential risks.
For breastfeeding, also see LactMed (National Library of Medicine), which summarizes milk levels and infant effects.
Supply and cost
Drug shortage status
Recalls (last 24 months)
Therapeutic equivalence (Orange Book)
Price ladder
Not the price at the counterThese are not what a patient pays at the pharmacy counter. They are what pharmacies, health plans, and government buyers pay, before manufacturer rebates. A patient's cost depends on their insurance (copay, coinsurance, or deductible) or the pharmacy's cash price.