Coding and coverage · ICD-10-CM

E16

E16.9 Disorder of pancreatic internal secretion, unspecified

BillableNo payment HCCChapter 4

Instructional notes

Chapter 4

Excludes1Not coded here: never report with this code, except when the two conditions are unrelated.
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Notes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

This code

Inclusion terms
  • Islet-cell hyperplasia NOS
  • Pancreatic endocrine cell hyperplasia NOS

Chapter 4: Endocrine, nutritional and metabolic diseases · E15-E16 Other disorders of glucose regulation and pancreatic internal secretion (E15-E16)

Source: ICD-10-CM FY 2027 code descriptions and tabular list (CMS and CDC National Center for Health Statistics), effective 2026-10-01 through 2027-09-30 · CMS ICD-10 files. HCC mapping: CMS-HCC V28, payment year 2027. As of 2026-11-04.

Coverage and payment depend on the claim details; confirm with the Medicare Administrative Contractor.