Coding and coverage · ICD-10-CM

E53

E53.1 Pyridoxine deficiency

BillableNo payment HCCChapter 4
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Instructional notes

Chapter 4

Excludes1Not coded here: never report with this code, except when the two conditions are unrelated.
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Notes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Section E50-E64

Excludes2Not included here: the patient may have both; report both when both are present.

E53

Excludes1Not coded here: never report with this code, except when the two conditions are unrelated.
  • sequelae of vitamin B deficiency (E64.8)

This code

Excludes1Not coded here: never report with this code, except when the two conditions are unrelated.
  • pyridoxine-responsive sideroblastic anemia (D64.3)
Inclusion terms
  • Vitamin B6 deficiency

Chapter 4: Endocrine, nutritional and metabolic diseases · E50-E64 Other nutritional deficiencies (E50-E64)

Source: ICD-10-CM FY 2027 code descriptions and tabular list (CMS and CDC National Center for Health Statistics), effective 2026-10-01 through 2027-09-30 · CMS ICD-10 files. HCC mapping: CMS-HCC V28, payment year 2027. As of 2026-11-04.

Coverage and payment depend on the claim details; confirm with the Medicare Administrative Contractor.