Coding and coverage · ICD-10-CM

Z17 Estrogen, and other hormones and factors receptor status

Not billable (header)Chapter 21

Report one of the more specific codes below.

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Codes under this one

  • Z17.0 Estrogen receptor positive status [ER+]
  • Z17.1 Estrogen receptor negative status [ER-]
  • Z17.2 Progesterone receptor statusHeader
  • Z17.3 Human epidermal growth factor 2 receptorHeader
  • Z17.4 Combined receptor statusHeader

Instructional notes

Chapter 21

Notes
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
  • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
  • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

This code

Code firstSequence the underlying condition first.
  • malignant neoplasm, such as:
  • malignant neoplasm of breast (C50.-)
  • malignant neoplasm of ovary (C56.-)
Notes

Chapter 21: Factors influencing health status and contact with health services · Z17 Estrogen, and other hormones and factors receptor status (Z17)

Source: ICD-10-CM FY 2027 code descriptions and tabular list (CMS and CDC National Center for Health Statistics), effective 2026-10-01 through 2027-09-30 · CMS ICD-10 files. HCC mapping: CMS-HCC V28, payment year 2027. As of 2026-11-04.

Coverage and payment depend on the claim details; confirm with the Medicare Administrative Contractor.