Coding and coverage · ICD-10-CM
Z16.3 Resistance to other antimicrobial drugs
Report one of the more specific codes below.
Codes under this one
- Z16.30 Resistance to unspecified antimicrobial drugs
- Z16.31 Resistance to antiparasitic drug(s)
- Z16.32 Resistance to antifungal drug(s)
- Z16.33 Resistance to antiviral drug(s)
- Z16.34 Resistance to antimycobacterial drug(s)Header
- Z16.35 Resistance to multiple antimicrobial drugs
- Z16.39 Resistance to other specified antimicrobial drug
Instructional notes
Chapter 21
Notes
- Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
- (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
- (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.
Z16
Excludes1Not coded here: never report with this code, except when the two conditions are unrelated.
Code firstSequence the underlying condition first.
- the infection
Notes
- The codes in this category are provided for use as additional codes to identify the resistance and non-responsiveness of a condition to antimicrobial drugs.
Chapter 21: Factors influencing health status and contact with health services · Z16 Resistance to antimicrobial drugs (Z16)
Source: ICD-10-CM FY 2027 code descriptions and tabular list (CMS and CDC National Center for Health Statistics), effective 2026-10-01 through 2027-09-30 · CMS ICD-10 files. HCC mapping: CMS-HCC V28, payment year 2027. As of 2026-11-04.
Coverage and payment depend on the claim details; confirm with the Medicare Administrative Contractor.