Coding and coverage · ICD-10-CM
D55.29 Anemia due to other disorders of glycolytic enzymes
Instructional notes
Chapter 3
Excludes2Not included here: the patient may have both; report both when both are present.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
D55
Excludes1Not coded here: never report with this code, except when the two conditions are unrelated.
- drug-induced enzyme deficiency anemia (D59.2)
D55.2
Excludes1Not coded here: never report with this code, except when the two conditions are unrelated.
- disorders of glycolysis not associated with anemia (E74.81-)
This code
Inclusion terms
- Hexokinase deficiency anemia
- Triose-phosphate isomerase deficiency anemia
Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism · D55-D59 Hemolytic anemias (D55-D59)
Source: ICD-10-CM FY 2027 code descriptions and tabular list (CMS and CDC National Center for Health Statistics), effective 2026-10-01 through 2027-09-30 · CMS ICD-10 files. HCC mapping: CMS-HCC V28, payment year 2027. As of 2026-11-04.
Coverage and payment depend on the claim details; confirm with the Medicare Administrative Contractor.