Coding and coverage · ICD-10-CM

D59 › D59.3

D59.39 Other hemolytic-uremic syndrome

BillableCMS-HCC V28: HCC 109Chapter 3
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Instructional notes

Chapter 3

Excludes2Not included here: the patient may have both; report both when both are present.
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

D59.3

Code also
  • , if applicable, any associated:
  • acute kidney failure (N17.-)
  • chronic kidney disease (N18.-)

This code

Code firstSequence the underlying condition first.
  • , if applicable, any associated:
  • COVID-19 (U07.1)
  • complications of kidney transplant (T86.1-)
  • complications of heart transplant (T86.2-)
  • complications of liver transplant (T86.4-)
Use additional codeAdd a second code for the full picture.
  • code, if applicable, for adverse effect to identify drug (T36-T50 with fifth or sixth character 5)
Code also
  • , if applicable, any associated condition, such as:
  • hypertensive emergency (I16.1)
  • malignant neoplasm (C00-C96)
  • systemic lupus erythematosus (M32.-)
Inclusion terms
  • Atypical (nongenetic) hemolytic uremic syndrome
  • Secondary hemolytic-uremic syndrome

Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism · D55-D59 Hemolytic anemias (D55-D59)

Source: ICD-10-CM FY 2027 code descriptions and tabular list (CMS and CDC National Center for Health Statistics), effective 2026-10-01 through 2027-09-30 · CMS ICD-10 files. HCC mapping: CMS-HCC V28, payment year 2027. As of 2026-11-04.

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