Coding and coverage · ICD-10-CM

M31 › M31.1

M31.11 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]

BillableCMS-HCC V28: HCC 454Chapter 13
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Instructional notes

Chapter 13

Excludes2Not included here: the patient may have both; report both when both are present.
  • arthropathic psoriasis (L40.5-)
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • compartment syndrome (traumatic) (T79.A-)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Notes
  • Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition

Section M30-M36

Excludes1Not coded here: never report with this code, except when the two conditions are unrelated.
  • autoimmune disease, single organ or single cell-type -code to relevant condition category
Includes
  • autoimmune disease NOS
  • collagen (vascular) disease NOS
  • systemic autoimmune disease
  • systemic collagen (vascular) disease

This code

Code firstSequence the underlying condition first.
  • if applicable:
  • complications of bone marrow transplant (T86.0-)
  • complications of stem cell transplant (T86.5)
Use additional codeAdd a second code for the full picture.
  • code to identify specific organ dysfunction, such as:
  • acute kidney failure (N17.-)
  • acute respiratory distress syndrome (J80)
  • capillary leak syndrome (I78.8)
  • diffuse alveolar hemorrhage (R04.89)
  • encephalopathy (metabolic) (septic) (G93.41)
  • fluid overload, unspecified (E87.70)
  • graft versus host disease (D89.81-)
  • hemolytic uremic syndrome (D59.3-)
  • hepatic failure (K72.-)
  • hepatic veno-occlusive disease (K76.5)
  • idiopathic interstitial pneumonia (J84.11-)
  • sinusoidal obstruction syndrome (K76.5)
Inclusion terms
  • Transplant-associated thrombotic microangiopathy [TA-TMA]

Chapter 13: Diseases of the musculoskeletal system and connective tissue · M30-M36 Systemic connective tissue disorders (M30-M36)

Source: ICD-10-CM FY 2027 code descriptions and tabular list (CMS and CDC National Center for Health Statistics), effective 2026-10-01 through 2027-09-30 · CMS ICD-10 files. HCC mapping: CMS-HCC V28, payment year 2027. As of 2026-11-04.

Coverage and payment depend on the claim details; confirm with the Medicare Administrative Contractor.