Rifampin 10 mg/mL oral suspension

Concentration

10 mg/mL

From

4 × 300 mg capsules

Vehicles named

Simple syrup (Syrup NF)

The label's instructions

Preparation of Extemporaneous Oral Suspension For pediatric and adult patients in whom capsule swallowing is difficult or where lower doses are needed, a liquid suspension may be prepared as follows: Rifampin 1% w/v suspension (10 mg/mL) can be compounded using one of four syrups–Simple Syrup (Syrup NF), Simple Syrup (Humco Laboratories), SyrPalta ®+ Syrup (Emerson Laboratories), or Raspberry Syrup (Humco Laboratories). Empty the contents of four rifampin capsules 300 mg or eight rifampin capsules 150 mg onto a piece of weighing paper. If necessary, gently crush the capsule contents with a spatula to produce a fine powder. Transfer the rifampin powder blend to a 4-ounce amber glass or plastic (high density polyethylene [HDPE], polypropylene, or polycarbonate) prescription bottle. Rinse the paper and spatula with 20 mL of one of the above-mentioned syrups, and add the rinse to the bottle. Shake vigorously. Add 100 mL of syrup to the bottle and shake vigorously. This compounding procedure results in a 1% w/v suspension containing 10 mg rifampin/mL. Stability studies indicate that the suspension is stable when stored at room temperature (25 ± 3°C) or in a refrigerator (2 to 8°C) for four weeks. This extemporaneously prepared suspension must be shaken well prior to administration.

Quoted verbatim from the Dosage and Administration section of the FDA label for rifampin, version 100, effective 2026-03-12. Open the label on DailyMed. 9 current labels for this drug carry these instructions.

Storage and beyond-use date

• “Stability studies indicate that the suspension is stable when stored at room temperature (25 ± 3°C) or in a refrigerator (2 to 8°C) for four weeks.”
• “Stability studies indicate that the suspension is stable when stored at room temperature (25 ± 3°C) or in a refrigerator (2 to 8°C) for four weeks.”

Only the storage conditions the source covers are listed. Use the BUD assistant for other cases. The BUD may not be later than any component's expiration date. Verify against the current official USP chapter.

Ingredient checks

No FDA compounding list or NIOSH flags for the active ingredient.

Source

FDA label (rifampin), Dosage and Administration.

For licensed clinicians. Use with clinical judgment.