Compounding

Nonsterile and sterile compounding tools in one place: beyond-use dates by USP chapter and section, master formulation and compounding records you can print, ingredient checks against FDA and NIOSH lists, and oral liquid formulas with their sources. Free, and nothing here needs an account.

Calculators

Every calculator shows its worked math, sources, and version.

• AlligationAlligation (mixing two strengths)Parts and amounts of a higher and a lower strength to make a desired strength.
• C1V1Dilution (C1V1 = C2V2)Volume of stock needed to prepare a target concentration and volume.
• % strengthPercent strength (w/v, w/w, v/v)Ingredient amount for a percent strength, or the percent strength of a preparation, with the ratio strength.
• 1:xRatio strength, percent, and mg/mL converterConverts between ratio strength (1:x), percent w/v, and mg/mL.
• mEq ↔ mgmg/mL, percent, mEq, and mmol converterConverts a salt concentration between mg/mL, percent w/v, mEq/mL, and mmol/mL from molecular weight and valence.
• mOsm/LMilliosmoles and osmolarity of a preparationIdeal osmolarity (mOsm/L) of a solution of up to two solutes from concentration, molecular weight, and particles.
• Supp DFSuppository base with a displacement factorBase and drug to weigh for a batch of suppositories from the mold's blank weight and the drug's displacement (density) factor.
• Capsule fillCapsule fill (volume and powder density)Diluent per capsule and for the batch from the capsule size, the drug amount, and the powders' bulk densities.
• Tabs → liquidOral liquid from tablets or capsulesTablets or capsules needed for a target concentration and volume, with the quantity of vehicle to add (q.s.).
• NaCl EIsotonicity (sodium chloride equivalent method)Sodium chloride (or another tonicity agent) needed to make a solution isotonic, using E values you enter.
• Powder volPowder volume and reconstitutionDiluent to add to a dry powder for a target concentration, accounting for the volume the powder occupies.
• AliquotAliquot method and minimum weighable quantityMinimum weighable quantity from balance sensitivity and acceptable error, and an aliquot plan for amounts below it.

Data behind these tools

• 366 nominated bulk substances (FDA, updated 2026-05-14)
• 85 withdrawn or removed products (21 CFR 216.24)
• 14 FDA label preparations
• 32 literature formulas

FDA lists refresh automatically each month. BUD rules follow the USP chapters official November 1, 2023; verify against the current official chapter. ClinDose does not reproduce USP, PCCA, Medisca, Trissel's, or Lexicomp content.

For licensed clinicians. Use with clinical judgment.