Literature: open-access stability study

Pyrimethamine 2 mg/mL oral suspension

Ingredients

IngredientRoleFor 100 mL
Pyrimethamineactive200 mg
Sorbitol 70% (w/v)vehicleq.s. to 100 mL
Strength
2 mg/mL
Starting material
Pyrimethamine 25 mg tablets
Container
See the study

Amounts are ClinDose's arithmetic from the study's concentration; follow the study for the method.

Storage and beyond-use date

StorageBUDBasis
Refrigerated45 daysCited stability study. Duration supported by the cited stability study for this formula, container, and storage.
Room temperature45 daysCited stability study. Duration supported by the cited stability study for this formula, container, and storage.

Only the storage conditions the source covers are listed. Use the BUD assistant for other cases. The BUD may not be later than any component's expiration date. Verify against the current official USP chapter.

Ingredient checks

No FDA compounding list or NIOSH flags for the active ingredient.

Source

de Paula RM, Santana VBS, Amorim MVP, et al.. Expiration Date of Extemporaneous Pyrimethamine Formulations for Treating Congenital Toxoplasmosis: Physicochemical and Microbiological Evaluation. ACS Omega. 2026;11(23):33582-33592. PMID 42326652. PMC13280895. License: CC BY (checked 2026-11-06). Read the article · DOI

For licensed clinicians. Use with clinical judgment.