Centruroides fab2 antivenin (equine)

FDA label, Rare Disease Therapeutics, Inc, intravenous, effective 2013-12-04. Full label on DailyMed

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From MedlinePlus, U.S. National Library of Medicine

Quoted from the FDA label. Product labels differ by manufacturer and change over time; confirm against the label for the product you are using.

Antivenin

Dosing in kidney impairment

This label has no separate kidney-impairment dosing section. Check warnings and clinical pharmacology in the full label.

Preparation and administration

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Initial Dose: 3 vials The initial dose of Anascorp is 3 vials. Reconstitute the contents of each vial with 5 milliliters of sterile normal saline and mix by continuous gentle swirling. Combine the contents of the reconstituted vials promptly and further dilute to a total volume of 50 milliliters with sterile normal saline.

Inspect the solution visually for particulate matter and discoloration prior to administration. Do not use if turbid. Infuse intravenously over 10 minutes. Monitor patient closely during and up to 60 minutes following the completion of infusion to determine if clinically important signs of envenomation have resolved. Discard partially used vials.

Initial Dose: 3 vials Additional doses may be used if needed. Infuse one vial at a time at intervals of 30 to 60 minutes. Reconstitute the contents with 5 milliliters of sterile normal saline and mix by continuous gentle swirling. Further dilute to a total volume of 50 milliliters with sterile normal saline. Inspect the solution visually for particulate matter or discoloration prior to administration.

Infuse intravenously over 10 minutes. Monitor patient closely during and up to 60 minutes following the completion of infusion to determine if clinically important signs of envenomation have resolved. Discard partially used vials.

Initial Dose 3 vials Reconstitute each vial with 5 milliliters of sterile normal saline. Combine and further dilute to a total of 50 milliliters. Infuse intravenously over 10 minutes.
Additional dose (s) As needed Administer one vial at a time at 30-60 minute intervals. Combine and further dilute to a total of 50 milliliters with sterile normal saline. Infuse intravenously over 10 minutes.

Drug interactions

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  • Centruroides fab2 antivenin (equine)
Label text (1 paragraph)

No drug interaction studies have been conducted with Anascorp.

Contraindications

None None.

Safety data

Reported adverse events (FAERS)

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Source: FDA Adverse Event Reporting System via openFDA

Liver injury (LiverTox)

LiverTox has no chapter for centruroides fab2 antivenin (equine). Check the label's hepatic warnings.

Supply and cost

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