Human clostridium tetani toxoid immune globulin

FDA label, GRIFOLS USA, LLC, intramuscular, effective 2010-10-28. Full label on DailyMed

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From MedlinePlus, U.S. National Library of Medicine

Quoted from the FDA label. Product labels differ by manufacturer and change over time; confirm against the label for the product you are using.

Dosing in kidney impairment

This label has no separate kidney-impairment dosing section. Check warnings and clinical pharmacology in the full label.

Preparation and administration

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Basis

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The dosage should be adjusted according to the severity of the infection. (7,8) Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. They should not be used if particulate matter and/or discoloration are present. Hyper TET S/D is supplied with a syringe and an attached UltraSafe ® Needle Guard for your protection and convenience.

Drug interactions

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  • Human clostridium tetani toxoid immune globulin
Label text (1 paragraph)

Drug Interactions Antibodies in immunoglobulin preparations may interfere with the response to live viral vaccines such as measles, mumps, polio, and rubella. Therefore, use of such vaccines should be deferred until approximately 3 months after Tetanus Immune Globulin (Human) — Hyper TET TM S/D administration. No interactions with other products are known.

Contraindications

None known.

Safety data

Reported adverse events (FAERS)

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Source: FDA Adverse Event Reporting System via openFDA

Liver injury (LiverTox)

LiverTox has no chapter for human clostridium tetani toxoid immune globulin. Check the label's hepatic warnings.

Pregnancy and lactation

Pregnancy

Pregnancy Category C Animal reproduction studies have not been conducted with Hyper TET S/D. It is also not known whether Hyper TET S/D can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Hyper TET S/D should be given to a pregnant woman only if clearly needed.

For breastfeeding, also see LactMed (National Library of Medicine), which summarizes milk levels and infant effects.

Supply and cost

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