Human c1-esterase inhibitor

  • Part D specialty tier in 77% of formularies (2026Q3)
  • Cinryze

Therapy management checklist

Screening, baseline and ongoing monitoring with the label's stated frequency, hold and discontinue criteria, and counseling points, each quoted from the FDA label.

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Storage and cold chain

Human c1-esterase inhibitor: storage and handling

Freezing
Do not freeze
Label statement
Do not freeze.
Room temperature
No allowance stated
Back into the refrigerator
Not addressed
Light
Not addressed
Shaking
Not addressed

Temperature excursion helper

Answers only from this label's storage statements. It does not judge whether a product is still usable beyond what the label states.

The label does not state a room-temperature allowance for this product.

Entered: 1 day at up to 77°F (25°C).

Do not freeze.

Contact the manufacturer about this product; the label text ClinDose has does not print a phone number for it.

All storage statements on the label (4)
  • CINRYZE, packaged for sale, is stable for 24 months when stored at 2°C–25°C (36°F-77°F).
  • Do not freeze.
  • Store the vial in the original carton to protect it from light.
  • Do not use beyond the expiration date on the CINRYZE vial.

FDA label version 10, effective November 1, 2010. DailyMed

Dosing and titration calendar

Built only from the schedules the label states (loading, titration, day schedules, cycles and weight bands). Steps the label states in words the calendar cannot place are shown, not guessed.

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Medicare Part D coverage

37%of plans list it
94%of those: prior authorization
0%step therapy
72%quantity limit
95%specialty tier

5,496 Part D plans, CMS formulary files 2026Q3. Look up tier, PA, step therapy and quantity limits by plan

Patient assistance

No manufacturer program page is listed for this drug yet.

Independent foundations and the full directory (checked 2026-11-06). Eligibility and amounts are set by each program; open its page for them.

For licensed clinicians. Use with clinical judgment. Statements are quoted from the FDA label; confirm against the label for the product you are using.