Insulin degludec and liraglutide
- Biologic
- Xultophy 100/3.6
Therapy management checklist
Screening, baseline and ongoing monitoring with the label's stated frequency, hold and discontinue criteria, and counseling points, each quoted from the FDA label.
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Storage and cold chain
Insulin degludec and liraglutide: storage and handling
- Refrigerate
- Yes, as the label states
Label statement
Prior to first use, XULTOPHY 100/3.6 should be stored between 36°F to 46°F (2°C and 8°C) until the expiration date printed on the label.
- Freezing
- Do not freeze
Label statement
Do not freeze.
- Room temperature
- up to 21 days at or below 30°C (86°F)
Label statement
After first use, the XULTOPHY 100/3.6 pen can be stored for 21 days at controlled room temperature 59°F to 86°F (15°C to 30°C) or in a refrigerator 36°F to 46°F (2°C to 8°C).
- Room temperature
- up to 21 days at or below 30°C (86°F)
Label statement
Conditions for XULTOPHY 100/3.6 Pen Prior to first use After first use Refrigerated 36°F to 46°F (2°C to 8°C) Room Temperature 59°F to 86°F (15°C to 30°C) Refrigerated 36°F to 46°F (2°C to 8°C) Until expiration date 21 Days
- Back into the refrigerator
- Not addressed
- Light
- Protect from light
Label statement
Store prefilled pens in the carton so they will stay clean and protected from light.
- Shaking
- Not addressed
All storage statements on the label (9)
- Prior to first use, XULTOPHY 100/3.6 should be stored between 36°F to 46°F (2°C and 8°C) until the expiration date printed on the label.
- Store prefilled pens in the carton so they will stay clean and protected from light.
- Do not store in the freezer or directly adjacent to the refrigerator cooling element.
- Do not freeze.
- Do not use XULTOPHY 100/3.6 if it has been frozen.
- After first use, the XULTOPHY 100/3.6 pen can be stored for 21 days at controlled room temperature 59°F to 86°F (15°C to 30°C) or in a refrigerator 36°F to 46°F (2°C to 8°C).
- Keep all XULTOPHY 100/3.6 pens away from direct heat and light.
- Always remove the needle after each injection and store the XULTOPHY 100/3.6 pen without a needle attached.
- Conditions for XULTOPHY 100/3.6 Pen Prior to first use After first use Refrigerated 36°F to 46°F (2°C to 8°C) Room Temperature 59°F to 86°F (15°C to 30°C) Refrigerated 36°F to 46°F (2°C to 8°C) Until expiration date 21 Days
FDA label version 14, effective October 14, 2025. DailyMed
Dosing and titration calendar
Built only from the schedules the label states (loading, titration, day schedules, cycles and weight bands). Steps the label states in words the calendar cannot place are shown, not guessed.
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Medicare Part D coverage
5,496 Part D plans, CMS formulary files 2026Q3. Look up tier, PA, step therapy and quantity limits by plan
Patient assistance
No manufacturer program page is listed for this drug yet.
Independent foundations and the full directory (checked 2026-11-06). Eligibility and amounts are set by each program; open its page for them.
For licensed clinicians. Use with clinical judgment. Statements are quoted from the FDA label; confirm against the label for the product you are using.