Interferon beta-1a subcutaneous

  • Part D specialty tier in 83% of formularies (2026Q3)
  • Biologic
  • REBIF

Therapy management checklist

Screening, baseline and ongoing monitoring with the label's stated frequency, hold and discontinue criteria, and counseling points, each quoted from the FDA label.

Loading the therapy management checklist…

Storage and cold chain

Interferon beta-1a subcutaneous: storage and handling

Refrigerate
Yes, as the label states
Label statement
REBIF should be stored refrigerated between 36°F to 46°F (2°C to 8°C).
Freezing
Do not freeze
Label statement
DO NOT FREEZE.
Room temperature
No allowance stated
Back into the refrigerator
Not addressed
Light
Not addressed
Shaking
Not addressed
Travel
Stated
Label statement
Storage 25 Travel 26 Notes 27 Rebif ® Rebidose ® features Before injection: After injection: Warnings Always use the injection technique advised by your health care provider and contact them with any questions you might have.

Temperature excursion helper

Answers only from this label's storage statements. It does not judge whether a product is still usable beyond what the label states.

The label does not state a room-temperature allowance for this product.

Entered: 1 day at up to 77°F (25°C).

REBIF should be stored refrigerated between 36°F to 46°F (2°C to 8°C).
DO NOT FREEZE.

Contact the manufacturer at 1-877-447-3243 (the number printed on the label) about this product.

Where the label prints this number
If at any time, you have questions or concerns, please contact your health care provider or call MS LifeLines at 1-877-447-3243.
All storage statements on the label (7)
  • REBIF should be stored refrigerated between 36°F to 46°F (2°C to 8°C).
  • DO NOT FREEZE.
  • If needed, REBIF may be stored between 36°F to 77°F (2°C to 25°C) for up to 30 days and away from heat and light, but refrigeration is preferred.
  • Do not use beyond the expiration date printed on packages.
  • Unused portions should be discarded.
  • Storage 25 Travel 26 Notes 27 Rebif ® Rebidose ® features Before injection: After injection: Warnings Always use the injection technique advised by your health care provider and contact them with any questions you might have.
  • Check the expiration date on the Rebidose ® autoinjector label and its carton.

FDA label version 27, effective September 22, 2025. DailyMed

Dosing and titration calendar

Built only from the schedules the label states (loading, titration, day schedules, cycles and weight bands). Steps the label states in words the calendar cannot place are shown, not guessed.

Loading dosing schedules…

Medicare Part D coverage

6%of plans list it
48%of those: prior authorization
12%step therapy
50%quantity limit
92%specialty tier

5,496 Part D plans, CMS formulary files 2026Q3. Look up tier, PA, step therapy and quantity limits by plan

Patient assistance

No manufacturer program page is listed for this drug yet.

Independent foundations and the full directory (checked 2026-11-06). Eligibility and amounts are set by each program; open its page for them.

For licensed clinicians. Use with clinical judgment. Statements are quoted from the FDA label; confirm against the label for the product you are using.