Mepolizumab
- Part D specialty tier in 75% of formularies (2026Q3)
- Biologic
- Nucala
Therapy management checklist
Screening, baseline and ongoing monitoring with the label's stated frequency, hold and discontinue criteria, and counseling points, each quoted from the FDA label.
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Storage and cold chain
Mepolizumab: storage and handling
- Refrigerate
- Yes, as the label states
Label statement
Prior to Dispensing: Refrigerate prefilled autoinjectors and prefilled syringes at 36°F to 46°F (2°C to 8°C).
- Freezing
- Do not freeze
Label statement
Do not freeze.
- Room temperature
- up to 7 days at or below 30°C (86°F)
Label statement
If necessary, an unopened carton can be stored outside the refrigerator at up to 86°F (30°C) for up to 7 days.
- Room temperature
- up to 7 days
Label statement
Discard if left out of the refrigerator for more than 7 days.
- Room temperature
- up to 7 days at or below 30°C (86°F)
Label statement
If necessary, an unopened carton can be stored outside the refrigerator at up to 86°F (30°C) for up to 7 days. .
- Room temperature
- up to 7 days
Label statement
Safely throw away the prefilled autoinjector if it is left out of the refrigerator in the unopened carton for more than 7 days. .
- Room temperature
- up to 7 days
Label statement
Safely throw away prefilled autoinjectors and prefilled syringes if the unopened carton is left out of the refrigerator for more than 7 days. .
- Back into the refrigerator
- Not addressed
- Light
- Protect from light
Label statement
Store in the original carton to protect from light.
- Shaking
- Do not shake
Label statement
Do not shake.
All storage statements on the label (21)
- Store vials below 77°F (25°C).
- Do not freeze.
- Store in the original carton to protect from light.
- Prior to Dispensing: Refrigerate prefilled autoinjectors and prefilled syringes at 36°F to 46°F (2°C to 8°C).
- Keep the product in the original carton to protect from light.
- Do not shake.
- Avoid exposure to heat.
- Following Dispensing: Refrigerate prefilled autoinjectors and prefilled syringes at 36°F to 46°F (2°C to 8°C).
- Keep the product in the original carton to protect from light until the time of use.
- If necessary, an unopened carton can be stored outside the refrigerator at up to 86°F (30°C) for up to 7 days.
- Discard if left out of the refrigerator for more than 7 days.
- Discard if not administered within 8 hours.
- Store in the refrigerator between 36°F to 46°F (2°C to 8°C). .
- Keep in the original carton until time of use to protect from light. .
- Keep away from heat. .
- If necessary, an unopened carton can be stored outside the refrigerator at up to 86°F (30°C) for up to 7 days. .
- Safely throw away the prefilled autoinjector if it is left out of the refrigerator in the unopened carton for more than 7 days. .
- How should I store NUCALA? .
- Store prefilled autoinjectors and prefilled syringes in the refrigerator between 36°F to 46°F (2°C to 8°C). .
- Keep prefilled autoinjectors and prefilled syringes in the original carton until time of use to protect from light. .
- Safely throw away prefilled autoinjectors and prefilled syringes if the unopened carton is left out of the refrigerator for more than 7 days. .
FDA label version 24, effective August 6, 2025. DailyMed
Dosing and titration calendar
Built only from the schedules the label states (loading, titration, day schedules, cycles and weight bands). Steps the label states in words the calendar cannot place are shown, not guessed.
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Medicare Part D coverage
5,496 Part D plans, CMS formulary files 2026Q3. Look up tier, PA, step therapy and quantity limits by plan
Patient assistance
No manufacturer program page is listed for this drug yet.
Independent foundations and the full directory (checked 2026-11-06). Eligibility and amounts are set by each program; open its page for them.
For licensed clinicians. Use with clinical judgment. Statements are quoted from the FDA label; confirm against the label for the product you are using.