Nedosiran
- Part D specialty tier in 84% of formularies (2026Q3)
- RIVFLOZA
Therapy management checklist
Screening, baseline and ongoing monitoring with the label's stated frequency, hold and discontinue criteria, and counseling points, each quoted from the FDA label.
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Storage and cold chain
Nedosiran: storage and handling
- Refrigerate
- Yes, as the label states
Label statement
Store refrigerated at 2°C to 8°C (36°F to 46°F).
- Freezing
- Do not freeze
Label statement
Do not freeze.
- Room temperature
- up to 28 days at or below 30°C (86°F)
Label statement
Table 4: Storage Conditions for RIVFLOZA Refrigerated 2°C to 8°C (36°F to 46°F) Room Temperature at 15°C to 30°C (59°F to 86°F) RIVFLOZA Until expiration date Maximum 28 days (4 weeks)
- Room temperature
- up to 28 days
Label statement
Record the date RIVFLOZA was removed from the refrigerator on the carton and throw away (dispose of) if not used within 28 days. .
- Back into the refrigerator
- Not addressed
- Light
- Protect from light
Label statement
Keep the RIVFLOZA Pre-filled Syringe in the carton and out of direct heat and sunlight. .
- Shaking
- Not addressed
All storage statements on the label (23)
- Store refrigerated at 2°C to 8°C (36°F to 46°F).
- RIVFLOZA can be stored, if needed, at 15°C to 30°C (59°F to 86°F) for a maximum of 28 days (4 weeks).
- Do not freeze.
- Store in original carton, away from direct heat and light.
- Table 4: Storage Conditions for RIVFLOZA Refrigerated 2°C to 8°C (36°F to 46°F) Room Temperature at 15°C to 30°C (59°F to 86°F) RIVFLOZA Until expiration date Maximum 28 days (4 weeks)
- How should I store RIVFLOZA Pre-filled Syringe? .
- Store unused RIVFLOZA Pre-filled Syringes in the refrigerator between 36°F to 46°F (2°C to 8°C). .
- If needed, RIVFLOZA Pre-filled Syringes can be stored between 59°F to 86°F (15°C to 30°C) for no longer than 28 days (4 weeks).
- Record the date RIVFLOZA was removed from the refrigerator on the carton and throw away (dispose of) if not used within 28 days. .
- Store RIVFLOZA Pre-filled Syringes in the original carton. .
- Keep RIVFLOZA Pre-filled Syringes away from direct heat and light. .
- Remove the RIVFLOZA Pre-filled Syringe carton from the refrigerator. .
- Check the expiration date on the carton.
- Do not use if the expiration date has passed. .
- Wait 30 minutes before injecting to allow the medicine in the Pre-filled Syringe to warm to room temperature.
- Keep the RIVFLOZA Pre-filled Syringe in the carton and out of direct heat and sunlight. .
- Do not warm the Pre-filled Syringe using any heat sources such as hot water or a microwave.
- How should I store RIVFLOZA? .
- Store RIVFLOZA in the refrigerator between 36°F to 46°F (2°C to 8°C). .
- If needed, RIVFLOZA can be stored between 59°F to 86°F (15°C to 30°C) for up to 28 days (4 weeks).
- Do not freeze RIVFLOZA. .
- Store RIVFLOZA in the original carton. .
- Keep RIVFLOZA away from direct heat and light.
FDA label version 4, effective March 3, 2025. DailyMed
Dosing and titration calendar
Built only from the schedules the label states (loading, titration, day schedules, cycles and weight bands). Steps the label states in words the calendar cannot place are shown, not guessed.
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Medicare Part D coverage
5,496 Part D plans, CMS formulary files 2026Q3. Look up tier, PA, step therapy and quantity limits by plan
Patient assistance
No manufacturer program page is listed for this drug yet.
Independent foundations and the full directory (checked 2026-11-06). Eligibility and amounts are set by each program; open its page for them.
For licensed clinicians. Use with clinical judgment. Statements are quoted from the FDA label; confirm against the label for the product you are using.