Olezarsen
- Part D specialty tier in 85% of formularies (2026Q3)
- TRYNGOLZA
Therapy management checklist
Screening, baseline and ongoing monitoring with the label's stated frequency, hold and discontinue criteria, and counseling points, each quoted from the FDA label.
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Storage and cold chain
Olezarsen: storage and handling
- Refrigerate
- Yes, as the label states
Label statement
Store the TRYNGOLZA autoinjector in the refrigerator between 2°C and 8°C (36°F and 46°F) in the original carton.
- Freezing
- Not addressed
- Room temperature
- up to 42 days at or below 30°C (86°F)
Label statement
Once taken out of the refrigerator, the TRYNGOLZA autoinjector can be stored at room temperature between 15°C and 30°C (59°F and 86°F) in the original carton for up to 6 weeks.
- Room temperature
- up to 42 days
Label statement
If not used within the 6 weeks stored at room temperature, discard TRYNGOLZA.
- Room temperature
- up to 42 days at or below 30°C (86°F)
Label statement
TRYNGOLZA can also be stored at room temperature between 59°F to 86°F (15°C to 30°C) in the original carton for up to 6 weeks.
- Room temperature
- up to 42 days
Label statement
Throw away the TRYNGOLZA autoinjector if kept at room temperature longer than 6 weeks .
- Back into the refrigerator
- Not addressed
- Light
- Protect from light
Label statement
Protect from light.
- Shaking
- Not addressed
All storage statements on the label (15)
- Store the TRYNGOLZA autoinjector in the refrigerator between 2°C and 8°C (36°F and 46°F) in the original carton.
- Once taken out of the refrigerator, the TRYNGOLZA autoinjector can be stored at room temperature between 15°C and 30°C (59°F and 86°F) in the original carton for up to 6 weeks.
- If not used within the 6 weeks stored at room temperature, discard TRYNGOLZA.
- Do not expose to heat.
- Protect from light.
- Storage information: Store the autoinjector in the refrigerator between 36°F to 46°F (2°C to 8°C) in the original carton.
- TRYNGOLZA can also be stored at room temperature between 59°F to 86°F (15°C to 30°C) in the original carton for up to 6 weeks.
- Do not let TRYNGOLZA reach temperatures above 86°F (30°C).
- Throw away the TRYNGOLZA autoinjector if kept at room temperature longer than 6 weeks .
- Do not expose the autoinjector to heat.
- Do not store the autoinjector with the clear cap removed.
- Parts of your TRYNGOLZA autoinjector Single-dose autoinjector Other supplies (not included) Alcohol wipe Sharps container Cotton ball or gauze Small bandage Preparing to inject TRYNGOLZA Step 1 Remove from the refrigerator a) Remove the autoinjector from the refrigerator. b) Keep the autoinjector in the original carton and let the autoinjector come to room temperature for 30 minutes before injecting.
- Do not try to speed up the warming process using other heat sources, such as a microwave or hot water.
- Store TRYNGOLZA autoinjector in the refrigerator between 36°F to 46°F (2°C to 8°C) in the original carton.
- Do not expose TRYNGOLZA autoinjector to heat.
FDA label version 7, effective July 3, 2026. DailyMed
Dosing and titration calendar
Built only from the schedules the label states (loading, titration, day schedules, cycles and weight bands). Steps the label states in words the calendar cannot place are shown, not guessed.
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Medicare Part D coverage
5,496 Part D plans, CMS formulary files 2026Q3. Look up tier, PA, step therapy and quantity limits by plan
Patient assistance
No manufacturer program page is listed for this drug yet.
Independent foundations and the full directory (checked 2026-11-06). Eligibility and amounts are set by each program; open its page for them.
For licensed clinicians. Use with clinical judgment. Statements are quoted from the FDA label; confirm against the label for the product you are using.