Peginterferon beta-1a

  • Part D specialty tier in 70% of formularies (2026Q3)
  • Biologic
  • Plegridy Pen

Therapy management checklist

Screening, baseline and ongoing monitoring with the label's stated frequency, hold and discontinue criteria, and counseling points, each quoted from the FDA label.

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Storage and cold chain

Peginterferon beta-1a: storage and handling

Refrigerate
Yes, as the label states
Label statement
Store PLEGRIDY prefilled pens and prefilled syringes in a refrigerator between 2°C to 8°C (36°F to 46°F) in the closed original carton to protect from light until ready for injection.
Freezing
Do not freeze
Label statement
Do not freeze.
Room temperature
up to 30 days at or below 25°C (77°F)
Label statement
If refrigeration is unavailable, PLEGRIDY may be stored at room temperature up to 25°C (77°F) for a period up to 30 days, protected from light.
Room temperature
up to 30 days
Label statement
The total combined time out of refrigeration should not exceed 30 days.
Room temperature
up to 30 days at or below 25°C (77°F)
Label statement
If a refrigerator is not available, PLEGRIDY may be stored at room temperature up to 77°F (25°C) for up to 30 days in total.
Back into the refrigerator
Not addressed
Light
Protect from light
Label statement
Store PLEGRIDY prefilled pens and prefilled syringes in a refrigerator between 2°C to 8°C (36°F to 46°F) in the closed original carton to protect from light until ready for injection.
Shaking
Not addressed

Temperature excursion helper

Answers only from this label's storage statements. It does not judge whether a product is still usable beyond what the label states.

Within the label's stated room-temperature allowance (up to 30 days at up to 25°C (77°F)). Follow the label's instructions for what to do next.

Entered: 1 day at up to 77°F (25°C).

If refrigeration is unavailable, PLEGRIDY may be stored at room temperature up to 25°C (77°F) for a period up to 30 days, protected from light.
Discard if frozen.

If anything else happened to the product, or you are unsure, Contact the manufacturer at 1-800-456-2255 (the number printed on the label) about this product.

Where the label prints this number
If you experience difficulty or have questions, call 1-800-456-2255.
All storage statements on the label (10)
  • Store PLEGRIDY prefilled pens and prefilled syringes in a refrigerator between 2°C to 8°C (36°F to 46°F) in the closed original carton to protect from light until ready for injection.
  • Do not freeze.
  • Discard if frozen.
  • If refrigeration is unavailable, PLEGRIDY may be stored at room temperature up to 25°C (77°F) for a period up to 30 days, protected from light.
  • PLEGRIDY can be removed from, and returned to, a refrigerator if necessary.
  • The total combined time out of refrigeration should not exceed 30 days.
  • Store Plegridy in the refrigerator between 36°F to 46°F (2°C to 8°C).
  • If a refrigerator is not available, PLEGRIDY may be stored at room temperature up to 77°F (25°C) for up to 30 days in total.
  • Keep Plegridy in the original carton to protect it from light.
  • Do not freeze Plegridy.

FDA label version 30, effective November 12, 2025. DailyMed

Dosing and titration calendar

Built only from the schedules the label states (loading, titration, day schedules, cycles and weight bands). Steps the label states in words the calendar cannot place are shown, not guessed.

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Medicare Part D coverage

13%of plans list it
83%of those: prior authorization
0%step therapy
95%quantity limit
85%specialty tier

5,496 Part D plans, CMS formulary files 2026Q3. Look up tier, PA, step therapy and quantity limits by plan

Patient assistance

No manufacturer program page is listed for this drug yet.

Independent foundations and the full directory (checked 2026-11-06). Eligibility and amounts are set by each program; open its page for them.

For licensed clinicians. Use with clinical judgment. Statements are quoted from the FDA label; confirm against the label for the product you are using.