Pegvisomant

  • Part D specialty tier in 80% of formularies (2026Q3)
  • Biologic
  • SOMAVERT

Therapy management checklist

Screening, baseline and ongoing monitoring with the label's stated frequency, hold and discontinue criteria, and counseling points, each quoted from the FDA label.

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Storage and cold chain

Pegvisomant: storage and handling

Refrigerate
Yes, as the label states
Label statement
The One Day Package of SOMAVERT should be stored in a refrigerator at 2°C to 8°C (36°F to 46°F). .
Freezing
Do not freeze
Label statement
Do not freeze.
Room temperature
up to 30 days at or below 25°C (77°F)
Label statement
For convenience, the One Day Package and intermediate cartons in the 30-Day Package containing the SOMAVERT vial(s), may be stored at room temperature up to 25°C (77°F) for a single period of up to 30 days. o In the space provided on the carton, record the date when the carton was removed from the refrigerator and the discard date (30 days after removal from the refrigerator). o Once the carton has been stored at room temperature, it should not be placed back into the refrigerator.
Room temperature
up to 30 days
Label statement
If not used within 30 days at room temperature, the vial(s) should be discarded.
Room temperature
at or below 30°C (86°F)
Label statement
The prefilled syringe(s) may be stored at a temperature up to 30°C (86°F) until the expiration date printed on the carton, at which point they should be discarded.
Room temperature
up to 30 days at or below 25°C (77°F)
Label statement
Before you mix the SOMAVERT powder and the liquid: o Store SOMAVERT in a refrigerator at 36°F to 46°F (2°C to 8°C). o The One Day Package and intermediate cartons in the 30-Day Package containing the SOMAVERT vials, may be stored at room temperature up to 77°F (25°C) for a single period of up to 30 days. o In the space provided on the carton, record the date when the carton was removed from the refrigerator and the discard date (30 days after removal from the refrigerator). o After the carton has been stored at room temperature, it should not be placed back into the refrigerator.
Room temperature
up to 30 days
Label statement
If not used within 30 days at room temperature, the vials should be thrown away. .
Room temperature
at or below 30°C (86°F)
Label statement
The prefilled syringes may be stored at a temperature up to 86°F (30°C) until the expiration date printed on the carton.
Room temperature
at or below 25°C (77°F)
Label statement
After you mix the SOMAVERT powder and liquid: o Keep the mixed SOMAVERT at room temperature between 59°F to 77°F (15°C to 25°C). o Keep SOMAVERT inside the vial or the syringe until you are ready to inject it. o You must use the mixed SOMAVERT immediately after you mix it . o If you have not used the mixed SOMAVERT immediately, throw it away.
Back into the refrigerator
Not allowed
Label statement
For convenience, the One Day Package and intermediate cartons in the 30-Day Package containing the SOMAVERT vial(s), may be stored at room temperature up to 25°C (77°F) for a single period of up to 30 days. o In the space provided on the carton, record the date when the carton was removed from the refrigerator and the discard date (30 days after removal from the refrigerator). o Once the carton has been stored at room temperature, it should not be placed back into the refrigerator.
Light
Not addressed
Shaking
Do not shake
Label statement
Include that spraying the diluent directly onto the powder may cause foaming and that shaking may induce denaturation (destruction) of the active ingredient (therefore do not shake ).

Temperature excursion helper

Answers only from this label's storage statements. It does not judge whether a product is still usable beyond what the label states.

Within the label's stated room-temperature allowance (up to 30 days at up to 25°C (77°F)). Follow the label's instructions for what to do next.

Entered: 1 day at up to 77°F (25°C).

For convenience, the One Day Package and intermediate cartons in the 30-Day Package containing the SOMAVERT vial(s), may be stored at room temperature up to 25°C (77°F) for a single period of up to 30 days. o In the space provided on the carton, record the date when the carton was removed from the refrigerator and the discard date (30 days after removal from the refrigerator). o Once the carton has been stored at room temperature, it should not be placed back into the refrigerator.
If not used within 30 days at room temperature, the vial(s) should be discarded.
Discard the SOMAVERT vial(s) after the expiration date printed on the carton or the discard date, whichever is sooner.
The prefilled syringe(s) may be stored at a temperature up to 30°C (86°F) until the expiration date printed on the carton, at which point they should be discarded.
Before you mix the SOMAVERT powder and the liquid: o Store SOMAVERT in a refrigerator at 36°F to 46°F (2°C to 8°C). o The One Day Package and intermediate cartons in the 30-Day Package containing the SOMAVERT vials, may be stored at room temperature up to 77°F (25°C) for a single period of up to 30 days. o In the space provided on the carton, record the date when the carton was removed from the refrigerator and the discard date (30 days after removal from the refrigerator). o After the carton has been stored at room temperature, it should not be placed back into the refrigerator.
Throw away the SOMAVERT vials after the expiration date printed on the carton or the discard date, whichever is sooner. .
After you mix the SOMAVERT powder and liquid: o Keep the mixed SOMAVERT at room temperature between 59°F to 77°F (15°C to 25°C). o Keep SOMAVERT inside the vial or the syringe until you are ready to inject it. o You must use the mixed SOMAVERT immediately after you mix it . o If you have not used the mixed SOMAVERT immediately, throw it away.

If anything else happened to the product, or you are unsure, Contact the manufacturer at 1-800-645-1280 (the number printed on the label) about this product.

Where the label prints this number
• Do not use if: o the medicine is cloudy or hazy o the medicine has any color at all o there are any particles or foam in the vial • If you have any doubts about your medication go to www.SOMAVERT.com or call 1-800-645-1280.
All storage statements on the label (15)
  • The One Day Package of SOMAVERT should be stored in a refrigerator at 2°C to 8°C (36°F to 46°F). .
  • For the 30-Day Package, remove the three intermediate cartons containing the SOMAVERT vials and store in a refrigerator at 2°C to 8°C (36°F to 46°F). .
  • For convenience, the One Day Package and intermediate cartons in the 30-Day Package containing the SOMAVERT vial(s), may be stored at room temperature up to 25°C (77°F) for a single period of up to 30 days. o In the space provided on the carton, record the date when the carton was removed from the refrigerator and the discard date (30 days after removal from the refrigerator). o Once the carton has been stored at room temperature, it should not be placed back into the refrigerator.
  • If not used within 30 days at room temperature, the vial(s) should be discarded.
  • Discard the SOMAVERT vial(s) after the expiration date printed on the carton or the discard date, whichever is sooner.
  • The prefilled syringe(s) may be stored at a temperature up to 30°C (86°F) until the expiration date printed on the carton, at which point they should be discarded.
  • Do not freeze.
  • How should I store SOMAVERT? .
  • Before you mix the SOMAVERT powder and the liquid: o Store SOMAVERT in a refrigerator at 36°F to 46°F (2°C to 8°C). o The One Day Package and intermediate cartons in the 30-Day Package containing the SOMAVERT vials, may be stored at room temperature up to 77°F (25°C) for a single period of up to 30 days. o In the space provided on the carton, record the date when the carton was removed from the refrigerator and the discard date (30 days after removal from the refrigerator). o After the carton has been stored at room temperature, it should not be placed back into the refrigerator.
  • If not used within 30 days at room temperature, the vials should be thrown away. .
  • Throw away the SOMAVERT vials after the expiration date printed on the carton or the discard date, whichever is sooner. .
  • The prefilled syringes may be stored at a temperature up to 86°F (30°C) until the expiration date printed on the carton.
  • Do not freeze SOMAVERT. .
  • After you mix the SOMAVERT powder and liquid: o Keep the mixed SOMAVERT at room temperature between 59°F to 77°F (15°C to 25°C). o Keep SOMAVERT inside the vial or the syringe until you are ready to inject it. o You must use the mixed SOMAVERT immediately after you mix it . o If you have not used the mixed SOMAVERT immediately, throw it away.
  • Include that spraying the diluent directly onto the powder may cause foaming and that shaking may induce denaturation (destruction) of the active ingredient (therefore do not shake ).

FDA label version 13, effective December 18, 2025. DailyMed

Dosing and titration calendar

Built only from the schedules the label states (loading, titration, day schedules, cycles and weight bands). Steps the label states in words the calendar cannot place are shown, not guessed.

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Medicare Part D coverage

100%of plans list it
97%of those: prior authorization
0%step therapy
40%quantity limit
97%specialty tier

5,496 Part D plans, CMS formulary files 2026Q3. Look up tier, PA, step therapy and quantity limits by plan

Patient assistance

No manufacturer program page is listed for this drug yet.

Independent foundations and the full directory (checked 2026-11-06). Eligibility and amounts are set by each program; open its page for them.

For licensed clinicians. Use with clinical judgment. Statements are quoted from the FDA label; confirm against the label for the product you are using.