Plozasiran

  • Part D specialty tier in 67% of formularies (2026Q3)
  • REDEMPLO

Therapy management checklist

Screening, baseline and ongoing monitoring with the label's stated frequency, hold and discontinue criteria, and counseling points, each quoted from the FDA label.

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Storage and cold chain

Plozasiran: storage and handling

Refrigerate
Yes, as the label states
Label statement
Store REDEMPLO refrigerated at 2°C to 8°C (36°F to 46°F) in the original carton, until ready for use.
Freezing
Not addressed
Room temperature
up to 30 days at or below 25°C (77°F)
Label statement
REDEMPLO prefilled syringe can also be kept at room temperature at 20°C to 25°C (68°F to 77°F) in the original carton for up to 30 days.
Room temperature
up to 30 days
Label statement
If not used within the 30 days stored at room temperature, discard REDEMPLO.
Room temperature
up to 30 days at or below 25°C (77°F)
Label statement
REDEMPLO prefilled syringe can also be stored at room temperature between 68°F to 77°F (20°C to 25°C) in the original carton for up to 30 days .
Room temperature
up to 30 days
Label statement
Throw away the REDEMPLO prefilled syringe if kept at room temperature and not used within 30 days.
Room temperature
up to 30 days at or below 25°C (77°F)
Label statement
REDEMPLO can also be stored at room temperature between 68°F to 77°F (20°C to 25°C) in the original carton for up to 30 days.
Room temperature
up to 30 days
Label statement
Throw away the REDEMPLO prefilled syringe if kept at room temperature longer than 30 days.
Back into the refrigerator
Not addressed
Light
Protect from light
Label statement
Storing REDEMPLO Keep the REDEMPLO prefilled syringe in the original carton until ready to use.
Shaking
Not addressed

Temperature excursion helper

Answers only from this label's storage statements. It does not judge whether a product is still usable beyond what the label states.

Within the label's stated room-temperature allowance (up to 30 days at up to 25°C (77°F)). Follow the label's instructions for what to do next.

Entered: 1 day at up to 77°F (25°C).

REDEMPLO prefilled syringe can also be kept at room temperature at 20°C to 25°C (68°F to 77°F) in the original carton for up to 30 days.
If not used within the 30 days stored at room temperature, discard REDEMPLO.
Throw away the REDEMPLO prefilled syringe if kept at room temperature and not used within 30 days.
If the product is not stored in any of the above conditions, throw away the prefilled syringe in a sharps disposal container and use a new prefilled syringe.
Throw away the REDEMPLO prefilled syringe if kept at room temperature longer than 30 days.

If anything else happened to the product, or you are unsure, Contact the manufacturer at 1-844-REDEMPLO (the number printed on the label) about this product.

Where the label prints this number
In any of the above cases, call 1-844-REDEMPLO or visit www.redemplo.com.
All storage statements on the label (13)
  • Store REDEMPLO refrigerated at 2°C to 8°C (36°F to 46°F) in the original carton, until ready for use.
  • REDEMPLO prefilled syringe can also be kept at room temperature at 20°C to 25°C (68°F to 77°F) in the original carton for up to 30 days.
  • If not used within the 30 days stored at room temperature, discard REDEMPLO.
  • Storing REDEMPLO Keep the REDEMPLO prefilled syringe in the original carton until ready to use.
  • Store the REDEMPLO prefilled syringe in the refrigerator between 36°F to 46°F (2°C to 8°C) in the original carton.
  • REDEMPLO prefilled syringe can also be stored at room temperature between 68°F to 77°F (20°C to 25°C) in the original carton for up to 30 days .
  • Do not let REDEMPLO reach temperatures above 77°F (25°C).
  • Throw away the REDEMPLO prefilled syringe if kept at room temperature and not used within 30 days.
  • If the product is not stored in any of the above conditions, throw away the prefilled syringe in a sharps disposal container and use a new prefilled syringe.
  • Preparing to Inject REDEMPLO Step 1: Gather all materials needed for your REDEMPLO injection Figure A On a clean, well-lit, flat work surface, place: Provided in the carton (see Figure A ): 1 REDEMPLO prefilled syringe Other materials not provided (see Figure A ): Alcohol wipes Cotton ball or gauze pad Adhesive bandage Sharps disposal container Step 2: Prepare to use REDEMPLO prefilled syringe Figure B Figure C Figure D If refrigerated, remove the carton from
  • Store REDEMPLO prefilled syringe in the refrigerator between 36°F to 46°F (2°C to 8°C) in the original carton, until you are ready to use.
  • REDEMPLO can also be stored at room temperature between 68°F to 77°F (20°C to 25°C) in the original carton for up to 30 days.
  • Throw away the REDEMPLO prefilled syringe if kept at room temperature longer than 30 days.

FDA label version 4, effective August 25, 2026. DailyMed

Dosing and titration calendar

Built only from the schedules the label states (loading, titration, day schedules, cycles and weight bands). Steps the label states in words the calendar cannot place are shown, not guessed.

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Medicare Part D coverage

2%of plans list it
100%of those: prior authorization
0%step therapy
100%quantity limit
92%specialty tier

5,496 Part D plans, CMS formulary files 2026Q3. Look up tier, PA, step therapy and quantity limits by plan

Patient assistance

No manufacturer program page is listed for this drug yet.

Independent foundations and the full directory (checked 2026-11-06). Eligibility and amounts are set by each program; open its page for them.

For licensed clinicians. Use with clinical judgment. Statements are quoted from the FDA label; confirm against the label for the product you are using.