Tocilizumab

  • Part D specialty tier in 80% of formularies (2026Q3)
  • Biologic
  • ACTEMRA

Therapy management checklist

Screening, baseline and ongoing monitoring with the label's stated frequency, hold and discontinue criteria, and counseling points, each quoted from the FDA label.

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Storage and cold chain

Tocilizumab: storage and handling

Refrigerate
Yes, as the label states
Label statement
ACTEMRA must be refrigerated at 36°F to 46°F (2ºC to 8ºC).
Freezing
Do not freeze
Label statement
Do not freeze.
Room temperature
up to 14 days at or below 30°C (86°F)
Label statement
Once removed from the refrigerator, the prefilled syringe and autoinjector can be stored up to 2 weeks at or below 86°F (30°C).
Back into the refrigerator
Not addressed
Light
Not addressed
Shaking
Not addressed

Temperature excursion helper

Answers only from this label's storage statements. It does not judge whether a product is still usable beyond what the label states.

Within the label's stated room-temperature allowance (up to 14 days at up to 30°C (86°F)). Follow the label's instructions for what to do next.

Entered: 1 day at up to 77°F (25°C).

Once removed from the refrigerator, the prefilled syringe and autoinjector can be stored up to 2 weeks at or below 86°F (30°C).

If anything else happened to the product, or you are unsure, Contact the manufacturer at 1-800-ACTEMRA (the number printed on the label) about this product.

Where the label prints this number
If you have questions or concerns about your ACTEMRA prefilled syringe, please contact your healthcare provider familiar with ACTEMRA or call 1-800-ACTEMRA.
All storage statements on the label (4)
  • Storage and Handling: Do not use beyond expiration date on the container, package, prefilled syringe, or autoinjector.
  • ACTEMRA must be refrigerated at 36°F to 46°F (2ºC to 8ºC).
  • Do not freeze.
  • Once removed from the refrigerator, the prefilled syringe and autoinjector can be stored up to 2 weeks at or below 86°F (30°C).

FDA label version 53, effective December 16, 2025. DailyMed

Dosing and titration calendar

Built only from the schedules the label states (loading, titration, day schedules, cycles and weight bands). Steps the label states in words the calendar cannot place are shown, not guessed.

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Biosimilars

Actemra: 5 licensed biosimilar products, 1 interchangeable (FDA Purple Book). Compare presentations and dates

Medicare Part D coverage

100%of plans list it
98%of those: prior authorization
0%step therapy
94%quantity limit
97%specialty tier

5,496 Part D plans, CMS formulary files 2026Q3. Look up tier, PA, step therapy and quantity limits by plan

Patient assistance

Independent foundations and the full directory (checked 2026-11-06). Eligibility and amounts are set by each program; open its page for them.

For licensed clinicians. Use with clinical judgment. Statements are quoted from the FDA label; confirm against the label for the product you are using.