Zilucoplan
- Part D specialty tier in 78% of formularies (2026Q3)
- ZILBRYSQ
Therapy management checklist
Screening, baseline and ongoing monitoring with the label's stated frequency, hold and discontinue criteria, and counseling points, each quoted from the FDA label.
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Storage and cold chain
Zilucoplan: storage and handling
- Refrigerate
- Yes, as the label states
Label statement
Pharmacy Prior to Dispensing Store ZILBRYSQ prefilled syringes refrigerated at 2°C to 8°C (36°F to 46°F) in the original carton until dispensing.
- Freezing
- Do not freeze
Label statement
Do not freeze.
- Room temperature
- up to 2190 hours at or below 30°C (86°F)
Label statement
Storage for Patients or Caregivers After Dispensing Storage conditions after dispensing by pharmacist are summarized in Table 4: Table 4: After Dispensing Storage Conditions Temperature Refrigeration 2°C to 8°C (36°F to 46°F) Room Temperature Up to 30°C (86°F) Time Period Until expiration date on the carton Up to 3 months after removing from refrigerator or until expiration date on the carton, whichever occurs first Do not freeze.
- Room temperature
- up to 2190 hours
Label statement
ZILBRYSQ prefilled syringes may be stored at room temperature in the original carton for a single period of up to 3 months.
- Room temperature
- up to 2190 hours
Label statement
When storing ZILBRYSQ prefilled syringes at room temperature, write the date removed from the refrigerator in the space provided on the carton and discard if not used within 3 months or if the expiration date has passed, whichever occurs first.
- Back into the refrigerator
- Not allowed
Label statement
Do not return ZILBRYSQ to the refrigerator after it has been stored at room temperature.
- Light
- Not addressed
- Shaking
- Not addressed
All storage statements on the label (8)
- Pharmacy Prior to Dispensing Store ZILBRYSQ prefilled syringes refrigerated at 2°C to 8°C (36°F to 46°F) in the original carton until dispensing.
- Do not freeze.
- Storage for Patients or Caregivers After Dispensing Storage conditions after dispensing by pharmacist are summarized in Table 4: Table 4: After Dispensing Storage Conditions Temperature Refrigeration 2°C to 8°C (36°F to 46°F) Room Temperature Up to 30°C (86°F) Time Period Until expiration date on the carton Up to 3 months after removing from refrigerator or until expiration date on the carton, whichever occurs first Do not freeze.
- Store ZILBRYSQ prefilled syringes in the original carton to protect them from light until time of use.
- ZILBRYSQ prefilled syringes may be stored at room temperature in the original carton for a single period of up to 3 months.
- When storing ZILBRYSQ prefilled syringes at room temperature, write the date removed from the refrigerator in the space provided on the carton and discard if not used within 3 months or if the expiration date has passed, whichever occurs first.
- Do not return ZILBRYSQ to the refrigerator after it has been stored at room temperature.
- ZILBRYSQ does not contain a preservative; discard any unused portion.
FDA label version 13, effective February 3, 2026. DailyMed
Dosing and titration calendar
Built only from the schedules the label states (loading, titration, day schedules, cycles and weight bands). Steps the label states in words the calendar cannot place are shown, not guessed.
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Medicare Part D coverage
5,496 Part D plans, CMS formulary files 2026Q3. Look up tier, PA, step therapy and quantity limits by plan
Patient assistance
No manufacturer program page is listed for this drug yet.
Independent foundations and the full directory (checked 2026-11-06). Eligibility and amounts are set by each program; open its page for them.
For licensed clinicians. Use with clinical judgment. Statements are quoted from the FDA label; confirm against the label for the product you are using.